Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752400 | 0.80 | LMNA (0.41) | ALDH1A1KMT2AKDM4ETSHRACHE | |
| SCHEMBL11749925 | 0.79 | LMNA (0.42) | ALDH1A1KMT2AKDM4EBCHEACHE | |
| SCHEMBL11752876 | 0.75 | TSHR (0.47) | ALDH1A1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL11750784 | 0.73 | BCHE (0.37) | ALDH1A1KMT2ABCHEACHELIPE | |
| SCHEMBL11751025 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2ABCHEACHELIPE | |
| SCHEMBL2914480 | 0.69 | MAPT (0.46) | ALDH1A1KMT2AKDM4ETSHRACHE | |
| SCHEMBL425007 | 0.67 | KMT2A (0.61) | ALDH1A1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL3584987 | 0.65 | SMN1; SMN2 (0.61) | ALDH1A1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL127188 | 0.65 | ELANE (0.43) | ALDH1A1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL28453399 | 0.64 | LMNA (0.42) | ALDH1A1KMT2AKDM4ETSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |