Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448369 | 0.70 | MEN1 (0.53) | RAB9ANPC1MEN1KMT2ASRD5A2 | |
| SCHEMBL197017 | 0.70 | LMNA (0.72) | RAB9ANPC1MEN1KMT2AGSTP1 | |
| SCHEMBL1855831 | 0.69 | MAOB (0.62) | RAB9ANPC1MEN1KMT2ASRD5A2 | |
| SCHEMBL28453850 | 0.68 | ALOX5 (0.49) | RAB9AGSTP1SRD5A2ALOX5MAOB | |
| SCHEMBL23483029 | 0.68 | LMNA (0.69) | RAB9ANPC1MEN1KMT2AGSTP1 | |
| SCHEMBL1096817 | 0.68 | LMNA (0.69) | RAB9ANPC1MEN1KMT2AGSTP1 | |
| SCHEMBL339813 | 0.68 | LMNA (0.82) | RAB9AGSTP1SRD5A2ALOX5MAOB | |
| SCHEMBL27367676 | 0.68 | LMNA (0.82) | RAB9AGSTP1SRD5A2ALOX5MAOB | |
| SCHEMBL9490004 | 0.68 | GSTP1 (0.54) | RAB9AGSTP1ALOX5MAOBLMNA | |
| SCHEMBL28500192 | 0.68 | MEN1 (0.57) | RAB9ANPC1MEN1KMT2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406424-B | Estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2020-08-25 | — | — | CN | disclosed |