Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293541 | 0.81 | LMNA (0.67) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL197017 | 0.81 | LMNA (0.72) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9489996 | 0.80 | GSTP1 (0.50) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28554319 | 0.79 | GSTP1 (0.55) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL12567822 | 0.79 | GSTP1 (0.55) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL23483029 | 0.79 | LMNA (0.69) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL1096817 | 0.79 | LMNA (0.69) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL22206787 | 0.79 | GSTP1 (0.58) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL12806827 | 0.78 | RXRA (0.60) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL2090546 | 0.78 | ALOX5 (0.53) | GSTP1LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219937-A | In presence of phosphite | ALLIEDSIGNAL INC. (US) | 1993-06-15 | — | — | US | disclosed |