SCHEMBL28458488

SCHEMBL28458488

CC(OC(C)(C)C)[SiH2]c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34
MAPK1 P28482 1/20 0.32
TAAR1 Q96RJ0 2/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10939962 0.75 RIPK1 (0.32) RIPK1
SCHEMBL14956638 0.71 L3MBTL1 (0.40) TAAR1
SCHEMBL8832572 0.69
SCHEMBL23630902 0.69 ALDH1A1 (0.36) MAPK1ALDH1A1
SCHEMBL6226657 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL780943 0.69 TAAR1 (0.39) RIPK1TAAR1
SCHEMBL705372 0.69
SCHEMBL2494267 0.68 HTR2A (0.36) MAPK1ALDH1A1ALOX15
Fluoride SCHEMBL27660868 0.67 MAOA (0.38) RIPK1TAAR1
Fluoride SCHEMBL27660869 0.67 MAOA (0.38) RIPK1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111542557-A Conjugated diene rubber 日本瑞翁株式会社 2020-08-14 CN disclosed