Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879057 | 0.90 | KMT2A (0.49) | KMT2AHSD17B10SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11709781 | 0.73 | KMT2A (0.43) | KMT2AHSD17B10RXFP1KDM4EALDH1A1 | |
| SCHEMBL31490429 | 0.71 | L3MBTL1 (0.63) | HSD17B10SMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL6111134 | 0.68 | KMT2A (0.51) | KMT2AHSD17B10RXFP1KDM4EALDH1A1 | |
| SCHEMBL22572568 | 0.67 | KMT2A (0.37) | KMT2AHSD17B10RXFP1KDM4EALDH1A1 | |
| SCHEMBL11881261 | 0.67 | MAP4K1 (0.33) | HSD17B10SMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL5950192 | 0.66 | HRH3 (0.43) | KMT2AHSD17B10SMN1; SMN2TSHRRXFP1 | |
| SCHEMBL8897917 | 0.66 | KMT2A (0.46) | KMT2AHSD17B10RXFP1KDM4EALDH1A1 | |
| SCHEMBL8026243 | 0.65 | ALDH1A1 (0.44) | KMT2AHSD17B10SMN1; SMN2CYP1A2TSHR | |
| SCHEMBL7836366 | 0.65 | ADRB2 (0.46) | SMN1; SMN2CYP3A4TSHRALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111727185-A | Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances | 拜耳公司 | 2020-09-29 | — | — | CN | disclosed |