Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960834 | 0.88 | ADRB2 (0.48) | ADRB2NCF1PLD1CHKADRD2 | |
| SCHEMBL30572331 | 0.83 | FPR2 (0.43) | ADRB2NCF1PLD1CHKADRD2 | |
| SCHEMBL2299228 | 0.82 | NPC1 (0.52) | DRD2ALDH1A1THRBCMA1MAPT | |
| SCHEMBL14491992 | 0.81 | DDB1 (0.53) | ALDH1A1USP2THRBSMN1; SMN2F10 | |
| Hydrochloric Acid SCHEMBL5314439 | 0.79 | DDB1 (0.51) | ALDH1A1USP2THRBSMN1; SMN2F10 | |
| SCHEMBL1259982 | 0.79 | ALDH1A1 (0.46) | DRD2ALDH1A1TSHRUSP2CMA1 | |
| SCHEMBL4626156 | 0.79 | FAAH (0.38) | ALDH1A1THRBSMN1; SMN2F10CMA1 | |
| SCHEMBL6324186 | 0.79 | RXFP1 (0.40) | ALDH1A1THRBSMN1; SMN2F10CMA1 | |
| SCHEMBL8286230 | 0.79 | SMN1; SMN2 (0.54) | DRD2ALDH1A1THRBSMN1; SMN2CMA1 | |
| SCHEMBL3783246 | 0.79 | CHRNB2 (0.57) | DRD2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719773-B1 | IMIDAZOLIDINONE DERIVATIVE, ACID-ADDITION SALT THEREOF, AND REMEDY FOR SENILE DEMENTIA | KYORIN SEIYAKU KK (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5789425-A | Imidazolidinone derivatives, their acid adducts and therapeutic drugs for senile dementia | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0719773-A1 | IMIDAZOLIDINONE DERIVATIVE, ACID-ADDITION SALT THEREOF, AND REMEDY FOR SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |