Sugi Predict

Sugi Predict / Compounds / Phenylalanine

Phenylalanine

Phenylalanine

SCHEMBL2544094

N[C@@H](Cc1ccccc1)C(=O)O.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 2/20 0.63
▸ ALPI P09923 1/20 0.63
▸ PKM P14618 1/20 0.63
▸ PTGS1 P23219 1/20 0.63
▸ XIAP P98170 1/20 0.63
▸ MMP2 P08253 1/20 0.55
▸ MC4R P32245 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.51
▸ NPC1 O15118 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ CRHBP P24387 1/20 0.50
▸ CRHR2 Q13324 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ ERAP2 Q6P179 1/20 0.50
▸ ERAP1 Q9NZ08 1/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ SLC1A3 P43003 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL5582272 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL27740947 0.99 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28464461 0.95 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28184207 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL5668485 0.88 MMP2 (0.53) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL503312 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26443 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26444 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL437181 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10903052 0.87 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132396-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS HENKEL AG & CO KGAA (DE) 2026-05-14 — — US disclosed
US-12606811-B2 Cleaning performance on protein sensitive soilings VI HENKEL AG & CO. KGAA (DE) 2026-04-21 — — US disclosed
EP-4695387-A1 VARIANT SUBTILISIN PROTEASES PEACCEL (FR) 2026-02-18 — — EP disclosed
US-20260028609-A1 PROTEASE VARIANTS WITH IMPROVED STORAGE STABILITY HENKEL AG & CO KGAA (DE) 2026-01-29 — — US disclosed
US-12492360-B2 Highly alkaline textile washing agent comprising protease HENKEL AG & CO. KGAA (DE) 2025-12-09 — — US disclosed
US-20250346835-A1 DETERGENT AND CLEANING AGENT WITH IMPROVED ENZYME STABILITY HENKEL AG & CO KGAA (DE) 2025-11-13 — — US disclosed
US-12415973-B2 Highly alkaline textile detergent comprising protease HENKEL AG & CO. KGAA (DE) 2025-09-16 — — US disclosed
US-12398386-B2 Stability-enhanced protease variants VI HENKEL AG & CO. KGAA (DE) 2025-08-26 — — US disclosed
US-12338469-B2 Proteases having improved enzyme stability in washing and cleaning agents III HENKEL AG & CO. KGAA (DE) 2025-06-24 — — US disclosed
WO-2025119569-A1 PROTEASE VARIANTS WITH IMPROVED BLEACH STABILITY HENKEL AG & CO. KGAA (DE) 2025-06-12 — — WO disclosed
US-20040038371-A1 Aminopeptidase DSM IP ASSETS B.V. (NL) 2004-02-26 — — US disclosed
US-20030215820-A1 Interleukins; aminopeptidases; blot analysis; drug screening GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2003-11-20 — — US disclosed
WO-2003084508-A1 DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE APPLIED NANOSYSTEMS B.V. (NL) 2003-10-16 — — WO disclosed
US-20030185938-A1 Targeting of active compounds to curd during cheese making DSM N.V. (NL) 2003-10-02 — — US disclosed
EP-1318723-A1 TARGETING OF ACTIVE COMPOUNDS TO CURD DURING CHEESE MAKING DSM N.V. (NL) 2003-06-18 — — EP disclosed
WO-2002023998-A1 TARGETING OF ACTIVE COMPOUNDS TO CURD DURING CHEESE MAKING DSM N.V. (NL) 2002-03-28 — — WO disclosed
WO-2002016618-A1 AMINOPEPTIDASE DSM N.V. (NL) 2002-02-28 — — WO disclosed
WO-2001064856-A2 REGULATORS OF TYPE-1 TUMOR NECROSIS FACTOR RECEPTOR AND OTHER CYTOKINE RECEPTOR SHEDDING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, A S REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEA LTH AND HUMAN SERVICES (US) 2001-09-07 — — WO disclosed
EP-0779780-A1 CLEANING, DISINFECTING AND PRESERVING CONTACT LENSES NOVO NORDISK A/S (DK) 1997-06-25 — — EP disclosed
WO-1996007324-A1 CLEANING, DISINFECTING AND PRESERVING CONTACT LENSES NOVO NORDISK A/S (DK) 1996-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606811-B2 Cleaning performance on protein sensitive soilings VI CTRL, SENP3, UCHL1 SLC7A5 2669/4885ALPI 63/4885PKM 4014/4885
US-20260132396-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS CTRL, DPEP1, MME SLC7A5 2589/4885ALPI 1092/4885PKM 4529/4885
US-20260028609-A1 PROTEASE VARIANTS WITH IMPROVED STORAGE STABILITY UBE2V1, CTRL, UCHL1 SLC7A5 3739/4885ALPI 447/4885PKM 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.