Sugi Predict

Sugi Predict / Compounds / Dl-Phenylalanine

Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL5582272

NC(Cc1ccccc1)C(=O)O.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 2/20 0.63
▸ ALPI P09923 1/20 0.63
▸ PKM P14618 1/20 0.63
▸ PTGS1 P23219 1/20 0.63
▸ XIAP P98170 1/20 0.63
▸ MMP2 P08253 1/20 0.55
▸ MC4R P32245 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.51
▸ NPC1 O15118 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ CRHBP P24387 1/20 0.50
▸ CRHR2 Q13324 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ ERAP2 Q6P179 1/20 0.50
▸ ERAP1 Q9NZ08 1/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ SLC1A3 P43003 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL2544094 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL27740947 0.99 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28464461 0.95 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28184207 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL5668485 0.88 MMP2 (0.53) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL503312 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26443 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26444 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL437181 0.88 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10903052 0.87 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116656655-A Aminopeptidase and coding gene thereof 江苏御娘食品有限公司 2023-08-29 — — CN disclosed
CN-116656655-A Aminopeptidase and coding gene thereof 江苏御娘食品有限公司 2023-08-29 — — CN disclosed
CN-103361287-B Producing strain of heat-resisting aminopeptidase and purification method of heat-resisting aminopeptidase UNIV JIANGNAN 2014-07-23 — — CN disclosed
CN-103361287-A Producing strain of heat-resisting aminopeptidase and purification method of heat-resisting aminopeptidase UNIV JIANGNAN 2013-10-23 — — CN disclosed
US-20070059758-A1 Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding THE GOVERNMENT OF THE USA OF AMERICA, REP. BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-03-15 — — US disclosed
US-7135303-B2 Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-11-14 — — US disclosed
WO-2006102069-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND GASTROINTESTINAL DISORDERS MICROBIA, INC. (US) 2006-09-28 — — WO disclosed
WO-2005074575-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS MICROBIA, INC. (US) 2005-08-18 — — WO disclosed
US-20030215820-A1 Interleukins; aminopeptidases; blot analysis; drug screening GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2003-11-20 — — US disclosed
WO-2001064856-A2 REGULATORS OF TYPE-1 TUMOR NECROSIS FACTOR RECEPTOR AND OTHER CYTOKINE RECEPTOR SHEDDING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, A S REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEA LTH AND HUMAN SERVICES (US) 2001-09-07 — — WO disclosed