Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050756 | 0.74 | ALDH1A1 (0.57) | P2RX7HPGDMEN1KMT2AFAAH | |
| SCHEMBL7705995 | 0.73 | P2RX7 (0.71) | P2RX7HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL13569125 | 0.73 | FAAH (0.65) | HPGDMEN1KMT2AFAAHNPSR1 | |
| SCHEMBL25447578 | 0.73 | P2RX7 (0.77) | P2RX7P2RX4NPSR1ALDH1A1MAPT | |
| SCHEMBL7661013 | 0.73 | P2RX7 (0.49) | P2RX7HPGDMEN1KMT2AP2RX4 | |
| SCHEMBL7661017 | 0.72 | HPGD (0.54) | P2RX7HPGDMEN1KMT2AP2RX4 | |
| SCHEMBL4599684 | 0.71 | KDM4E (0.54) | P2RX7HPGDMEN1KMT2AFAAH | |
| SCHEMBL5923737 | 0.71 | P2RX7 (1.00) | P2RX7HPGDMEN1KMT2AMAPK1 | |
| SCHEMBL13276034 | 0.71 | FAAH (0.53) | P2RX7HPGDMEN1KMT2AFAAH | |
| SCHEMBL1150351 | 0.71 | USP2 (0.52) | P2RX7HPGDMEN1KMT2AP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |