Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419229 | 0.86 | MEN1 (0.59) | ALDH1A1KDM4ETSHRHTTP2RX7 | |
| SCHEMBL13148549 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4ETSHRHTTFAAH | |
| SCHEMBL13052367 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRHTTFAAH | |
| SCHEMBL11259126 | 0.81 | LMNA (0.46) | ALDH1A1KDM4ETSHRHTTFAAH | |
| SCHEMBL539067 | 0.81 | RAB9A (0.57) | ALDH1A1HTTP2RX7CNR2LMNA | |
| SCHEMBL27837991 | 0.81 | KMT2A (0.62) | ALDH1A1KDM4EHTTP2RX7HSD11B1 | |
| SCHEMBL4599684 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4ETSHRHTTFAAH | |
| SCHEMBL27574792 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4ETSHRHTTFAAH | |
| SCHEMBL8581921 | 0.78 | CNR2 (0.63) | ALDH1A1KDM4EP2RX7HPGDCNR2 | |
| Benzamide SCHEMBL28953881 | 0.78 | TSHR (0.55) | ALDH1A1KDM4ETSHRHTTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946180-A | Chiral iridium complex and preparation method and application thereof | 南方科技大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-111056890-B | Method for preparing aryl ketone by free radical-free radical coupling reaction of ketoacid decarboxylation and fatty aldehyde decarbonylation based on iron catalysis | 湘潭大学 | 2022-10-14 | — | — | CN | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-0946440-B1 | 2-ADAMANTYL BENZOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING INC (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6099759-A | USED IN PHOTOCHROMIC OPHTHALMIC ARTICLES SUCH AS LENSES | CORNING INCORPORATED (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0946440-A4 | 2-ADAMANTYL BENZOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING INC (US) | 2000-03-22 | — | — | EP | disclosed |
| CN-1241170-A | 2-adamantyl benzopyrans, composition and (co)polymer matrixes contg. them | CORNING INC (US) | 2000-01-12 | — | — | CN | disclosed |
| EP-0946440-A1 | 2-ADAMANTYL BENZOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING INCORPORATED (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5888432-A | PHOTOCHROMIC COMPOUNDS | CORNING INCORPORATED (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998028235-A1 | 2-ADAMANTYL BENZOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING INCORPORATED (US) | 1998-07-02 | — | — | WO | disclosed |
| US-4200588-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC | THE UPJOHN COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4130561-A | Polycycloanilines | THE UPJOHN COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4120899-A | HYPOLIPEDEMIC, ANTIATHEROSCLEROTIC | THE UPJOHN COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4036977-A | HYPOLIPEDEMIC AND ANTIATHEROSCLEROTIC PROPERTIES | THE UPJOHN COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | ALDH1A1 874/4885KDM4E 377/4885TSHR 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.