SCHEMBL28466396

SCHEMBL28466396

CCCc1ccc(B(O)O)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 8/20 0.53
LIPG Q9Y5X9 8/20 0.53
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
SKP2 Q13309 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
FFAR4 Q5NUL3 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
MGLL Q99685 1/20 0.39
ALOX5 P09917 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CYP4Z1 Q86W10 1/20 0.37
CYP4F11 Q9HBI6 1/20 0.37
CYP4F12 Q9HCS2 1/20 0.37
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31591871 0.85 LIPG (0.59) LPLLIPGSKP2CA1CA2
SCHEMBL13885830 0.83 LPL (0.50) LPLLIPGCA1CA2ALOX5
SCHEMBL6487851 0.79 ENPP2 (0.45) LPLLIPGESR1ESR2
SCHEMBL29653353 0.79 ENPP2 (0.45) LPLLIPGESR1ESR2
SCHEMBL2483099 0.78 LPL (0.52) LPLLIPGCNR1CNR2CA1
SCHEMBL16576672 0.78 ESR1 (0.45) LPLLIPGSKP2CA1CA2
SCHEMBL24803737 0.78 F11 (0.47) LPLLIPGCYP3A4ESR1ESR2
SCHEMBL598650 0.76 CNR1 (0.50) LPLLIPGCNR1CNR2SKP2
SCHEMBL27207974 0.76 SLC6A2 (0.44) LPLLIPGSKP2CA1CA2
SCHEMBL332894 0.75 CNR1 (0.67) CNR1CNR2ALOX5CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825534-A Liquid crystal compound and preparation method and application thereof 北京八亿时空液晶科技股份有限公司 2020-10-27 CN disclosed