Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487851 | 1.00 | ENPP2 (0.45) | ENPP2HSD17B10ESR1ESR2LPL | |
| SCHEMBL29653364 | 0.83 | ENPP2 (0.45) | ENPP2HSD17B10ESR1ESR2LPL | |
| SCHEMBL24456142 | 0.83 | ENPP2 (0.45) | ENPP2HSD17B10ESR1ESR2LPL | |
| SCHEMBL13885830 | 0.83 | LPL (0.50) | HSD17B10ESR1ESR2LPLLIPG | |
| SCHEMBL24803737 | 0.81 | F11 (0.47) | ENPP2ESR1ESR2LPLLIPG | |
| SCHEMBL28466396 | 0.79 | LPL (0.53) | ESR1ESR2LPLLIPG | |
| SCHEMBL3784877 | 0.78 | ENPP2 (0.45) | ENPP2HSD17B10LPLLIPGSHBG | |
| SCHEMBL16576672 | 0.78 | ESR1 (0.45) | HSD17B10ESR1ESR2LPLLIPG | |
| SCHEMBL2295096 | 0.77 | ENPP2 (0.44) | ENPP2HSD17B10LPLLIPGCYP4F2 | |
| SCHEMBL29730087 | 0.77 | ENPP2 (0.44) | ENPP2HSD17B10LPLLIPGCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001886-A1 | ENPP1 INHIBITORS I | RE VENTURES I LLC (US) | 2026-01-01 | — | — | US | disclosed |
| WO-2025233863-A1 | ENPP1 INHIBITORS | RE VENTURES I, LLC (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2022250104-A1 | QUINOLONE DERIVATIVE HAVING ANTIMALARIAL ACTIVITY | 国立大学法人長崎大学 | 2022-12-01 | — | — | WO | disclosed |
| EP-4069696-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-10-12 | — | — | EP | disclosed |
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001886-A1 | ENPP1 INHIBITORS I | ENPP1, ENPP2, ENPP3 | ENPP2 2/4885HSD17B10 1767/4885ESR1 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.