Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848772 | 1.00 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL2852624 | 1.00 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL2846775 | 0.89 | ALDH1A1 (0.40) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL4527292 | 0.83 | LMNA (0.40) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL27285703 | 0.82 | FDPS (0.45) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL22921051 | 0.82 | LMNA (0.43) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL3233199 | 0.80 | LMNA (0.42) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL4457163 | 0.80 | TSHR (0.57) | TSHRGGPS1THRBFDPSCES2 | |
| Alcohol SCHEMBL14672676 | 0.77 | FDPS (0.45) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL29685628 | 0.77 | FDPS (0.41) | LMNATSHRALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2159274-B1 | BRAKE FLUID CONTAINING TETRAZOLE | CHIYODA CHEMICAL CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-8357642-B2 | Functional fluid | CHIYODA CHEMICAL CO., LTD. (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20100137174-A1 | FUNCTIONAL FLUID | CHIYODA CHEMICAL CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2159274-A1 | FUNCTIONAL FLUID | Chiyoda Chemical Co. Ltd (JP) | 2010-03-03 | — | — | EP | disclosed |