Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019388 | 0.82 | TOP1 (0.49) | TOP1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL28847907 | 0.79 | ABCB11 (0.39) | HTTALDH1A1KMT2ATDP1POLB | |
| SCHEMBL23621178 | 0.79 | MEN1 (0.48) | TOP1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL7067974 | 0.79 | TSHR (0.53) | TOP1KDM4EALDH1A1GAATNFSF11 | |
| SCHEMBL9713692 | 0.77 | HTT (0.47) | TOP1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL19995438 | 0.77 | PIM1 (0.42) | KDM4EALDH1A1MAPTGAATSHR | |
| SCHEMBL27001691 | 0.77 | ACHE (0.54) | HTTKDM4EALDH1A1MAPTGAA | |
| SCHEMBL14659690 | 0.76 | CYP19A1 (0.46) | KDM4EALDH1A1MAPTKMT2APOLB | |
| SCHEMBL10053943 | 0.75 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL8765614 | 0.75 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191662-B | Mangosteen alcohol derivative and application thereof | 石家庄学院 | 2020-10-23 | — | — | CN | disclosed |