Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469598 | 0.86 | NFE2L2 (0.45) | ALDH1A1KDM4EHPGDNPC1CASP3 | |
| SCHEMBL28475130 | 0.85 | CASP3 (0.48) | ALDH1A1KDM4EHPGDNPC1CASP3 | |
| SCHEMBL28465814 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDRELACASP3 | |
| SCHEMBL28475013 | 0.84 | NFE2L2 (0.53) | RELANPC1NFE2L2CYP1A2 | |
| SCHEMBL28245595 | 0.84 | NFE2L2 (0.53) | RELANPC1NFE2L2CYP1A2 | |
| SCHEMBL28822929 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDPTGS1PTGS2 | |
| SCHEMBL28481152 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDALOX5NPC1 | |
| SCHEMBL28471394 | 0.78 | NFE2L2 (0.45) | ALDH1A1KDM4EHPGDNPC1CASP3 | |
| SCHEMBL28465811 | 0.78 | RELA (0.49) | KDM4EHPGDRELANPC1RAB9A | |
| SCHEMBL28478476 | 0.78 | MAOA (0.52) | ALDH1A1KDM4EHPGDPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727294-B | Stilbene compound containing thiazole ring and synthesis method and application thereof | 浙江工业大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-108605949-B | Application of stilbene compound containing thiazole ring as bactericide | 浙江工业大学 | 2020-12-15 | — | — | CN | disclosed |
| CN-108863977-B | Stilbene compound containing bromothiazole ring and synthesis method and application thereof | 浙江工业大学 | 2020-09-22 | — | — | CN | disclosed |