Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28704543 | 0.93 | VCP (0.58) | VCPFFAR1L3MBTL1TDP1KMT2A | |
| SCHEMBL28479005 | 0.88 | FFAR1 (0.58) | VCPFFAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL28480057 | 0.83 | L3MBTL1 (0.57) | FFAR1L3MBTL1TDP1KMT2ACNR2 | |
| SCHEMBL28824705 | 0.83 | FFAR1 (0.50) | FFAR1L3MBTL1CNR2SMN1; SMN2NPC1 | |
| SCHEMBL28754059 | 0.83 | RAB9A (0.54) | FFAR1L3MBTL1TDP1KMT2ACNR2 | |
| SCHEMBL29162927 | 0.83 | FFAR1 (0.52) | VCPFFAR1L3MBTL1NPC1RAB9A | |
| SCHEMBL28704538 | 0.77 | FFAR1 (0.54) | FFAR1L3MBTL1CNR2NPC1RAB9A | |
| SCHEMBL28689949 | 0.77 | FFAR1 (0.54) | FFAR1L3MBTL1KMT2ACNR1CNR2 | |
| SCHEMBL28685979 | 0.77 | FFAR1 (0.54) | FFAR1L3MBTL1TDP1KMT2ACNR1 | |
| SCHEMBL28824698 | 0.76 | NPC1 (0.57) | FFAR1L3MBTL1TDP1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892597-B | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 山西天宏达安医药科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-111892597-A | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | claimed |
| CN-111892597-B | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 山西天宏达安医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-110698426-B | Method for preparing 1, 3-benzothiazole derivative by efficient catalysis of potassium tert-butoxide | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-111892597-A | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | disclosed |
| CN-110698426-A | Method for preparing 1, 3-benzothiazole derivative by efficient catalysis of potassium tert-butoxide | 陕西师范大学 | 2020-01-17 | — | — | CN | disclosed |