Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28754059 | 0.94 | RAB9A (0.54) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL28479005 | 0.84 | FFAR1 (0.58) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL28704543 | 0.83 | VCP (0.58) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL28704538 | 0.80 | FFAR1 (0.54) | NPC1RAB9AFFAR1ALDH1A1EGFR | |
| SCHEMBL28685979 | 0.80 | FFAR1 (0.54) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL28689949 | 0.80 | FFAR1 (0.54) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL6241316 | 0.79 | NPC1 (0.65) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL10069798 | 0.76 | APP (0.72) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL28470683 | 0.76 | VCP (0.54) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL30814290 | 0.76 | L3MBTL1 (0.51) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183397-B | Method for preparing 1, 5-benzothiazine compound by catalysis of zirconocene dichloride | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |