Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471016 | 0.88 | MAPKAPK2 (0.51) | MAPTALDH1A1SMN1; SMN2KDM4EABCB1 | |
| SCHEMBL30148069 | 0.88 | MAPKAPK2 (0.51) | MAPTALDH1A1SMN1; SMN2KDM4EABCB1 | |
| SCHEMBL28475885 | 0.83 | LMNA (0.48) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL28464316 | 0.77 | GUSB (0.39) | GAAPOLBKDM4EABCB1ABCG2 | |
| SCHEMBL28899922 | 0.77 | GUSB (0.39) | LMNAGAAALDH1A1ABCB1ABCG2 | |
| SCHEMBL29630294 | 0.75 | LMNA (0.61) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL9401163 | 0.73 | LMNA (0.70) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL28470333 | 0.73 | LMNA (0.74) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL12831402 | 0.71 | HDAC1 (0.61) | LMNAMEN1KMT2AMAPTGAA | |
| SCHEMBL28464327 | 0.71 | LMNA (0.58) | LMNAMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675725-B | Tetrahydro-beta-carbaline dimer and preparation method and application thereof | 中国药科大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-111675725-A | Tetrahydro-beta-carbaline dimer and preparation method and application thereof | 中国药科大学 | 2020-09-18 | — | — | CN | disclosed |