Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468946 | 0.79 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL28476136 | 0.78 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL20161261 | 0.74 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL28689541 | 0.74 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL20138345 | 0.74 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL29136717 | 0.73 | CYP2A6 (0.35) | RIPK1 | |
| SCHEMBL28938984 | 0.73 | ALDH1A1 (0.43) | RIPK1 | |
| SCHEMBL30090447 | 0.73 | CYP2A6 (0.35) | RIPK1 | |
| Hydrochloric Acid SCHEMBL28469788 | 0.73 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL18248292 | 0.72 | RIPK1 (0.71) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370452-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107624111-B | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-11-03 | — | — | CN | disclosed |