Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490028 | 0.74 | AKR1B1 (0.39) | ALDH1A1MAPTAKR1B1SMN1; SMN2APEX1 | |
| SCHEMBL5668472 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTAKR1B1APEX1PKM | |
| SCHEMBL20362157 | 0.71 | APEX1 (0.33) | ALDH1A1AKR1B1APEX1PKMKMT2A | |
| SCHEMBL29051906 | 0.70 | APEX1 (0.35) | ALDH1A1AKR1B1APEX1PKMKMT2A | |
| SCHEMBL8599400 | 0.69 | KIF11 (0.32) | AKR1B1 | |
| SCHEMBL3807640 | 0.69 | HTT (0.34) | HTTALDH1A1MAPTITGA4AKR1B1 | |
| SCHEMBL28486941 | 0.67 | IDO1 (0.37) | ALDH1A1MAPTAKR1B1POLBSMN1; SMN2 | |
| SCHEMBL28679428 | 0.67 | MAPT (0.38) | HTTALDH1A1MAPTITGA4POLB | |
| SCHEMBL4625185 | 0.67 | MAPT (0.34) | ALDH1A1MAPTITGA4SMN1; SMN2PKM | |
| SCHEMBL28301722 | 0.66 | THRB (0.39) | ALDH1A1APEX1LMNAALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111380979-A | Healthy aged diagnosis marker and application | 中国科学院昆明动物研究所 | 2020-07-07 | — | — | CN | disclosed |