Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599400 | 0.77 | KIF11 (0.32) | AKR1B1 | |
| SCHEMBL2490028 | 0.74 | AKR1B1 (0.39) | APEX1PKMKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL5668472 | 0.73 | ALDH1A1 (0.38) | APEX1PKMKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL20362157 | 0.71 | APEX1 (0.33) | APEX1PKMKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL28472018 | 0.70 | HTT (0.34) | APEX1PKMKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL29051887 | 0.69 | APEX1 (0.41) | APEX1PKMKMT2AAKR1B1ALDH1A1 | |
| SCHEMBL11801474 | 0.68 | MAOA (0.35) | ALDH1A1 | |
| SCHEMBL28301722 | 0.66 | THRB (0.39) | APEX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27357806 | 0.66 | TSHR (0.35) | KMT2AALDH1A1 | |
| SCHEMBL571992 | 0.65 | APEX1 (0.33) | APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116430047-A | Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |