Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985073 | 0.80 | GSK3B (0.67) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL25827018 | 0.80 | HPGD (0.57) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL326104 | 0.79 | MAPT (0.50) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL7835720 | 0.79 | KMT2A (0.69) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL1031237 | 0.79 | HPGD (0.73) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL14229126 | 0.76 | CCR2 (0.58) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL18931677 | 0.72 | HPGD (0.55) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL18931683 | 0.71 | HPGD (0.51) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7847653 | 0.71 | HPGD (0.51) | HPGDKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL18931674 | 0.71 | ALDH1A1 (0.51) | HPGDKMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909100-B | Method for preparing uracil and thymine derivatives | 武汉大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-111909100-A | Method for efficiently preparing uracil and thymine derivatives | 武汉大学 | 2020-11-10 | — | — | CN | disclosed |