SCHEMBL28474667

SCHEMBL28474667

C=CC(=O)Oc1ccc(-c2ccccc2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
BACE1 P56817 4/20 0.43
EGFR P00533 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
RAB9A P51151 1/20 0.41
THRB P10828 2/20 0.41
POLB P06746 1/20 0.40
PELI1 Q96FA3 1/20 0.40
EPHX1 P07099 1/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PDE6D O43924 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL27826386 0.87 BACE1 (0.44) BACE1EGFRALDH1A1HPGDHSD17B10
SCHEMBL11225929 0.86 THRB (0.47) EGFRALDH1A1HPGDHSD17B10NPC1
SCHEMBL16191264 0.86 ALOX15 (0.44) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL28781870 0.84 CSNK2A1 (0.41) BACE1BCL2L1NPC1MEN1KMT2A
SCHEMBL18472419 0.84 PTGS1 (0.46) BACE1HPGDNPC1MEN1KMT2A
SCHEMBL23161028 0.82 HPGD (0.47) BACE1EGFRALDH1A1HPGDBCL2L1
SCHEMBL28288566 0.81 ALOX5 (0.47) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL3824865 0.80 BACE1 (0.63) ALOX5BACE1EGFRALDH1A1NPC1
Hydrogen Sulfide SCHEMBL27808065 0.80 THRB (0.46) BACE1NPC1MEN1KMT2AKDM4E
SCHEMBL20925168 0.79 PDE6D (0.46) BACE1NPC1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108101786-B Method for synthesizing phenoxyalkenyl ether compound by catalyzing palladium salt 西南大学 2020-09-22 CN disclosed