Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21170004 | 0.88 | THRB (0.47) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL28474667 | 0.86 | ALOX5 (0.50) | THRBNPC1RAB9AMEN1MAPT | |
| SCHEMBL28476797 | 0.83 | THRB (0.44) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL8512513 | 0.83 | NPC1 (0.58) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL10694878 | 0.83 | THRB (0.47) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL31169459 | 0.83 | NPC1 (0.58) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL28475721 | 0.83 | THRB (0.44) | THRBALDH5A1ABATCYP3A4NPC1 | |
| SCHEMBL819722 | 0.83 | THRB (0.53) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL68673 | 0.82 | KMT2A (0.50) | THRBCYP3A4NPC1RAB9AMEN1 | |
| SCHEMBL15338917 | 0.82 | THRB (0.46) | THRBCYP3A4MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366171-A | Fungicidal biphenyl esters, mixtures thereof and method of use | GAF CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |