Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847813 | 1.00 | MAPK8 (0.42) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL7062547 | 0.91 | MAPK8 (0.43) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL29356745 | 0.91 | MAPK8 (0.43) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL202888 | 0.91 | MAPK8 (0.43) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL8357800 | 0.90 | GCK (0.36) | MAPK8MAPK10GCKRAB9AMEN1 | |
| SCHEMBL2847819 | 0.90 | MAPK8 (0.45) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL3165254 | 0.87 | POLB (0.39) | RAB9AGAATSHRALDH1A1PYGL | |
| SCHEMBL3165244 | 0.87 | POLB (0.39) | RAB9AGAATSHRALDH1A1PYGL | |
| SCHEMBL7062543 | 0.84 | MAPK8 (0.45) | MAPK8MAPK10GCKTDP1CTNNB1 | |
| SCHEMBL2108009 | 0.83 | SRC (0.36) | MAPK8MAPK10MEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043600-B2 | Microbiocidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-20240041028-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | OMYA INTERNATIONAL AG (CH) | 2024-02-08 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| EP-4271185-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | Omya International AG (CH) | 2023-11-08 | — | — | EP | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| EP-3717479-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3941898-B1 | FUNGICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3244732-B1 | USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS | OMYA INT AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5990043-A | COMPRISES AT LEAST ONE INSECTICIDE SELECTED FROM TRIFLUMURON, FLUFENOXURON, FLUCYCLOXURON, HEXAFLUMURON, AND OTHERS; A CARRIER AND BINDER; PROTECTS ITEMS SUCH AS SHIP HULLS IN BRACKISH OR SEAWATER FROM BARNICLE INFESTATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5703103-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| US-5672617-A | Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| WO-1997001547-A1 | BENZAZOLE DERIVATIVES WITH MICROBIOCIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | MAPK8 4040/4885MAPK10 4468/4885GCK 4495/4885 |
| US-12043600-B2 | Microbiocidal compounds | MPO, MSR1, PRF1 | MAPK8 4405/4885MAPK10 3665/4885GCK 2373/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | MAPK8 4519/4885MAPK10 3992/4885GCK 1898/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | MAPK8 3452/4885MAPK10 3875/4885GCK 695/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | MAPK8 3441/4885MAPK10 1169/4885GCK 968/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | MAPK8 4376/4885MAPK10 4264/4885GCK 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.