Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28508991 | 0.99 | OPRM1 (0.35) | OPRM1OPRK1OPRD1KDM4EMEN1 | |
| SCHEMBL8865254 | 0.78 | OPRM1 (0.36) | OPRM1OPRK1 | |
| SCHEMBL9074802 | 0.77 | PNMT (0.44) | ADRA2AADRA2BADRA2C | |
| SCHEMBL28513726 | 0.75 | OPRM1 (0.36) | OPRM1OPRK1 | |
| SCHEMBL5827252 | 0.72 | ADRA1A (0.44) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27796359 | 0.71 | CYP19A1 (0.46) | OPRM1ADRA2AADRA2BADRA2CADRA1B | |
| Hydrochloric Acid SCHEMBL8614363 | 0.71 | ADRA1A (0.43) | MEN1KMT2A | |
| SCHEMBL6667416 | 0.69 | OPRM1 (0.34) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6250927 | 0.68 | ADRA1A (0.54) | OPRM1MEN1ALDH1A1KMT2AADRA2A | |
| SCHEMBL28489574 | 0.67 | SLC6A2 (0.37) | ADRA2AADRA2BADRA2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925330-A | Preparation method of altimezole | 上海阿达玛斯试剂有限公司 | 2020-11-13 | — | — | CN | disclosed |