Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513726 | 0.78 | OPRM1 (0.36) | OPRM1OPRK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28478349 | 0.78 | OPRM1 (0.36) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL28508991 | 0.77 | OPRM1 (0.35) | OPRM1OPRK1 | |
| SCHEMBL5827252 | 0.72 | ADRA1A (0.44) | P2RX7CHRNB2CHRNA4 | |
| SCHEMBL6250927 | 0.71 | ADRA1A (0.54) | OPRM1 | |
| Hydrochloric Acid SCHEMBL8614363 | 0.70 | ADRA1A (0.43) | P2RX7ANPEPCHRNB2CHRNA4 | |
| SCHEMBL9354789 | 0.69 | F2R (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL769063 | 0.68 | ADRA1A (0.55) | OPRM1 | |
| SCHEMBL3234004 | 0.67 | OPRM1 (0.49) | OPRM1ANPEPOPRK1GRIN2DGRIN3B | |
| SCHEMBL16691788 | 0.67 | OPRM1 (0.34) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658938-A | HYPOTENSIVE AGENT, ANTIISCHMIC AGENTS | U C B S.A. (BE) | 1997-08-19 | — | — | US | disclosed |
| EP-0717037-A1 | Substituted 1H-imidazoles having alpha 2-agonistic and alpha 1-antagonistic activity | U C B, S.A. (BE) | 1996-06-19 | — | — | EP | disclosed |