Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865254 | 0.78 | OPRM1 (0.36) | OPRM1OPRK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28478349 | 0.75 | OPRM1 (0.36) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL28508991 | 0.74 | OPRM1 (0.35) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5827252 | 0.69 | ADRA1A (0.44) | CHRNB2CHRNA4 | |
| SCHEMBL6250927 | 0.68 | ADRA1A (0.54) | OPRM1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8614363 | 0.67 | ADRA1A (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL9354789 | 0.66 | F2R (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24821349 | 0.65 | PRCP (0.42) | OPRM1PRCPGRIN2DGRIN3BGRIN1 | |
| SCHEMBL769063 | 0.65 | ADRA1A (0.55) | OPRM1 | |
| SCHEMBL29222708 | 0.63 | ADRA1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225700-B | Preparation method of atemezole | 湖南新合新生物医药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112225700-A | Preparation method of altimezole | 湖南新合新生物医药有限公司 | 2021-01-15 | — | — | CN | disclosed |