Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162985 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4EMRGPRX4F2TDP1 | |
| SCHEMBL9159636 | 0.86 | TDP1 (0.53) | ALDH1A1MRGPRX4TDP1HTTMEN1 | |
| SCHEMBL11091005 | 0.83 | ACHE (0.45) | ALDH1A1KDM4EMRGPRX4TDP1TP53 | |
| SCHEMBL11343615 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EMRGPRX4F2TDP1 | |
| SCHEMBL11093890 | 0.81 | MEN1 (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL28781871 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EMRGPRX4F2TDP1 | |
| SCHEMBL11601543 | 0.79 | LMNA (0.49) | ALDH1A1TDP1HTTKMT2ALMNA | |
| SCHEMBL10779004 | 0.79 | CYP1A2 (0.55) | ALDH1A1KDM4EMRGPRX4TDP1HTT | |
| SCHEMBL11221532 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EMRGPRX4TDP1HTT | |
| SCHEMBL11091140 | 0.78 | PTK2B (0.45) | TDP1HTTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5352821-A | Reacting 2,4,5-trichlorobenzenesulfonate with thioglycolic acid in presence of base, reacting with mineral acid or aqueous solution thereof | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-10-04 | — | — | US | claimed |
| EP-0496396-A2 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1992-07-29 | — | — | EP | claimed |
| EP-0290886-B1 | PROCESS FOR THE PREPARATION OF 2,5-DICHLOROPHENYLTHIOGLYCOLIC ACID | CASSELLA Aktiengesellschaft (DE) | 1992-01-08 | — | — | EP | claimed |
| US-4555580-A | FROM PHENYLTHIOGLYCOLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | claimed |
| JP-5086019-A | — | — | None | — | — | JP | disclosed |
| JP-5178816-A | — | — | None | — | — | JP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0488237-B1 | Method for producing dichlorophenylthioglycolic acid | SUMITOMO SEIKA CHEMICALS (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4652660-A | OXIDATION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4617403-A | Process for preparing a pigment based on 4,4',7,7'-tetrachlorothioindigo | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | disclosed |
| US-4555580-A | FROM PHENYLTHIOGLYCOLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |
| US-4431824-A | Preparation of 4,4',7,7'-tetrachlorothioindigo pigments of high color strength | BASF AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | disclosed |
| US-4332955-A | Preparation of transparent pigmentary forms of 4,4',7,7'-tetrachlorothioindigo | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4260778-A | Process for the preparation of thioindigo compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4209469-A | CATALYTIC HYDROGENATION OF ARYL SULFOCHLORIDE | CIBA-GEIGY AG (CH) | 1980-06-24 | — | — | US | disclosed |