SCHEMBL28478574

SCHEMBL28478574

OSC1=Cc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CYP11B2 P19099 2/20 0.37
PTGS2 P35354 2/20 0.37
CYP11B1 P15538 1/20 0.37
TRPA1 O75762 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
ACHE P22303 1/20 0.34
IP6K1 Q92551 1/20 0.34
IP6K3 Q96PC2 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
HTR1A P08908 1/20 0.33
HTR2A P28223 1/20 0.33
HTR7 P34969 1/20 0.33
DRD3 P35462 1/20 0.33
HTR2B P41595 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7199649 0.78 PTGS2 (0.41) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL7191958 0.75 MAOA (0.41) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL7194834 0.71 POLB (0.39) MAOAMAOBMTNR1AMTNR1BACHE
SCHEMBL275380 0.70 MAOA (0.47) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL30664496 0.69 PTGS2 (0.57) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL7205941 0.69 PTGS2 (0.57) MAOAMAOBCYP11B2PTGS2CYP11B1
Hydrochloric Acid SCHEMBL11420101 0.68 MAOA (0.46) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL2627028 0.68 CYP11B2 (0.43) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL1577673 0.67 CYP11B2 (0.46) MAOAMAOBCYP11B2PTGS2CYP11B1
SCHEMBL626635 0.67 MAOA (0.44) MAOAMAOBCYP11B2PTGS2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107635676-B Pretreatment method for electroless plating 麦克德米德股份有限公司 2020-09-18 CN disclosed