Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478574 | 0.78 | MAOA (0.43) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL7191958 | 0.75 | MAOA (0.41) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL7196687 | 0.72 | SOAT1 (0.39) | PTGS2ACHEMTNR1AMTNR1B | |
| SCHEMBL2970211 | 0.72 | TRPA1 (0.39) | TRPA1HTR2AHTR2BCA1CA2 | |
| SCHEMBL19493795 | 0.72 | SIGMAR1 (0.35) | CYP11B2CYP11B1CA1CA2 | |
| SCHEMBL319633 | 0.72 | PTGS2 (0.46) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL29370486 | 0.72 | PTGS2 (0.46) | PTGS2MAOAMAOBACHECYP11B2 | |
| SCHEMBL7194834 | 0.71 | POLB (0.39) | MAOAMAOBACHEMTNR1AMTNR1B | |
| Bromide SCHEMBL31108155 | 0.70 | PTGS2 (0.44) | PTGS2MAOAMAOBACHECYP11B2 | |
| Lithium SCHEMBL29594699 | 0.70 | PTGS2 (0.44) | PTGS2MAOAMAOBACHECYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055766-A | Magic and non-magic serotonin receptor agonist and its preparing process and usage | 库莱恩有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114669077-B | Purification system and purification method of 2-methylnaphthalene | 煤炭科学技术研究院有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114669077-A | Purification system and purification method of 2-methylnaphthalene | 煤炭科学技术研究院有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20180079727-A1 | 9-MEMBERED FUSED RING DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-100506762-C | Purification method of beta-methylnaphthalene | BAOSHAN & IRON STEEL CO LTD (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-101028988-A | Purification method of beta-methylnaphthalene | BAOSHAN & IRON STEEL CO LTD (CN) | 2007-09-05 | — | — | CN | disclosed |
| EP-0668865-B1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM NV (NL) | 2003-07-23 | — | — | EP | disclosed |
| US-5990253-A | METALLOCENES HAVING THE INDENE RING BINDING AT THE 2-POSITION RATHER THAN AT THE 1-POSITION; COORDINATION CATALYSTS; LESS CRYSTALLIZATION IN THE ADDITION POLYMERIZATION OF ELASTOMERS | DSM N.V. (NL) | 1999-11-23 | — | — | US | disclosed |
| US-5646322-A | Indenyl compounds and catalyst components for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| EP-0668865-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011406-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079727-A1 | 9-MEMBERED FUSED RING DERIVATIVE | ACSS2, AGTR2, ACSL3 | PTGS2 2320/4885MAOA 1625/4885MAOB 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.