Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358097 | 0.82 | THRB (0.36) | NOS2THRBRECQLMEN1USP2 | |
| SCHEMBL111094 | 0.82 | THRB (0.36) | NOS2THRBRECQLMEN1USP2 | |
| Hydrochloric Acid SCHEMBL19549198 | 0.80 | MAPT (0.39) | NOS2THRBRECQLMEN1USP2 | |
| SCHEMBL6946033 | 0.80 | THRB (0.35) | NOS2THRBRECQLMEN1USP2 | |
| SCHEMBL11402718 | 0.78 | PDE2A (0.39) | NOS2THRBRECQLMEN1USP2 | |
| SCHEMBL19972208 | 0.78 | THRB (0.34) | NOS2THRBRECQLMEN1USP2 | |
| SCHEMBL30120579 | 0.78 | PDE2A (0.39) | NOS2THRBRECQLMEN1USP2 | |
| Sulfuric Acid SCHEMBL6947452 | 0.74 | ALDH1A1 (0.50) | THRBRECQLMEN1USP2POLB | |
| SCHEMBL9638692 | 0.72 | THRB (0.35) | THRBRECQLMEN1USP2POLB | |
| SCHEMBL446559 | 0.71 | ALDH1A1 (0.41) | THRBRECQLMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443890-B1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | HENKEL AG & CO KGAA (DE) | 2010-01-13 | — | — | EP | claimed |
| EP-1139989-B1 | AGENT FOR COLORING KERATINACEOUS FIBERS | HENKEL KGAA (DE) | 2006-10-18 | — | — | EP | claimed |
| US-6743263-B1 | Method for coloring keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-01 | — | — | US | claimed |
| EP-1443890-B1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | HENKEL AG & CO KGAA (DE) | 2010-01-13 | — | — | EP | disclosed |
| EP-1139989-B1 | AGENT FOR COLORING KERATINACEOUS FIBERS | HENKEL KGAA (DE) | 2006-10-18 | — | — | EP | disclosed |
| US-6743263-B1 | Method for coloring keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-01 | — | — | US | disclosed |