Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602537 | 0.82 | TSHR (0.36) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL446559 | 0.74 | ALDH1A1 (0.41) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL29940754 | 0.74 | ALDH1A1 (0.41) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL111094 | 0.72 | THRB (0.36) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL11584910 | 0.72 | CASP1 (0.38) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL29358097 | 0.72 | THRB (0.36) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL2847906 | 0.72 | NOS2 (0.36) | THRBRECQLTDP1MEN1USP2 | |
| Hydrochloric Acid SCHEMBL19549198 | 0.71 | MAPT (0.39) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL6946033 | 0.71 | THRB (0.35) | THRBRECQLTDP1MEN1USP2 | |
| SCHEMBL7865964 | 0.69 | THRB (0.34) | THRBRECQLTDP1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395726-B1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | AlliedSignal Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0395726-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS. | ALLIED SIGNAL INC (US) | 1990-11-07 | — | — | EP | disclosed |
| WO-1989008160-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | ALLIED-SIGNAL INC. (US) | 1989-09-08 | — | — | WO | disclosed |
| US-4839124-A | Reduction of carboxyl end groups in polyester fibers with lactim ethers | ALLIED-SIGNAL INC. (US) | 1989-06-13 | — | — | US | disclosed |