Sulfisomidine

Sulfisomidine

SCHEMBL284793

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.97
AGO2 Q9UKV8 1/20 0.97
ALDH1A1 P00352 6/20 0.68
KDM4E B2RXH2 3/20 0.68
LMNA P02545 2/20 0.68
CYP3A4 P08684 3/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
HTR6 P50406 5/20 0.59
POLB P06746 3/20 0.58
MAPT P10636 3/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
RAB9A P51151 1/20 0.58
ADRA1A P35348 1/20 0.57
USP2 O75604 1/20 0.57
APEX1 P27695 1/20 0.57
BLM P54132 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfisomidine SCHEMBL34791 0.98 PDE4A (1.00) PDE4AAGO2ALDH1A1KDM4ELMNA
Sulfamethazine SCHEMBL28086389 0.92 PDE4A (0.87) PDE4AAGO2ALDH1A1KDM4ELMNA
SCHEMBL1828300 0.84 PDE4A (0.74) PDE4AAGO2ALDH1A1KDM4ELMNA
SCHEMBL1381858 0.83 PDE4A (0.73) PDE4AAGO2ALDH1A1KDM4ELMNA
SCHEMBL5453637 0.82 PDE4A (0.71) PDE4AAGO2ALDH1A1KDM4ELMNA
Sulfametomidine SCHEMBL30336540 0.82 HTR6 (0.76) PDE4AAGO2ALDH1A1KDM4ELMNA
Sulfametomidine SCHEMBL151238 0.82 HTR6 (0.76) PDE4AAGO2ALDH1A1KDM4ELMNA
Sulfametomidine SCHEMBL11123046 0.81 ALDH1A1 (0.74) PDE4AAGO2ALDH1A1KDM4ELMNA
SCHEMBL11757838 0.81 PDE4A (0.69) PDE4AAGO2ALDH1A1KDM4ELMNA
Sulfamethazine SCHEMBL1442165 0.80 ALDH1A1 (0.97) PDE4AAGO2ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3111920-B1 COMPOSITION FOR PROMOTING HAIR GROWTH AND/OR HAIR RESTORATION CONTAINING SULFA AGENT AND CHITOSAN AGENT GREENEVER (JP) 2019-08-28 EP claimed
US-20170128379-A1 MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS RUBICON RESEARCH PRIVATE LIMITED (IN) 2017-05-11 US claimed
US-20170014327-A1 COMPOSITION FOR PROMOTING HAIR RESTORATION AND/OR HAIR GROWTH CONTAINING SULFA AGENT AND CHITOSAN AGENT GREENEVER (JP) 2017-01-19 US claimed
EP-3111920-A1 COMPOSITION FOR PROMOTING HAIR GROWTH AND/OR HAIR RESTORATION CONTAINING SULFA AGENT AND CHITOSAN AGENT Greenever (JP) 2017-01-04 EP claimed
US-20160325012-A1 GEL-FORMING AGENT COMPRISING SULFA AGENT AND CHITOSAN AGENT AND HAVING POWDERED DOSAGE FORM GREENEVER (JP) 2016-11-10 US claimed
EP-3087990-A1 GEL-FORMING AGENT CONTAINING SULFONAMIDE AND CHITOSAN AND HAVING A POWDERED DOSAGE FORM Greenever (JP) 2016-11-02 EP claimed
WO-2016001937-A2 MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS RUBICON RESEARCH PRIVATE LIMITED (IN) 2016-01-07 WO claimed
JP-10295777-A None JP disclosed
JP-9301873-A None JP disclosed
EP-4620988-A1 COPOLYMER, AND COMPOSITION FOR EYES NOF Corporation (JP) 2025-09-24 EP disclosed
US-20250206863-A1 COPOLYMER AND CONTACT LENS TREATMENT SOLUTION NOF CORPORATION (JP) 2025-06-26 US disclosed
WO-2024262353-A1 COMPOSITION FOR ORAL CAVITY ライオン株式会社 2024-12-26 WO disclosed
WO-2024135344-A1 OPHTHALMIC PRODUCT ライオン株式会社 2024-06-27 WO disclosed
WO-1987006226-A2 AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATIONS CONTAINING THE ABSORPTION PROMOTERS HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1987-10-22 WO disclosed
EP-0241050-A2 Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparation containing the absorption promoters HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1987-10-14 EP disclosed
EP-0123948-B1 EXTERNAL PHARMACEUTICAL COMPOSITION TEIJIN LIMITED (JP) 1987-09-30 EP disclosed
EP-0227836-A1 SUSTAINED RELEASING PATCH TEIJIN LIMITED (JP) 1987-07-08 EP disclosed
US-4670185-A ANIONIC, CATIONIC, NONIONIC SURFACTANTS LION CORPORATION (JP) 1987-06-02 US disclosed
EP-0173990-A2 External pharmaceutical composition TEIJIN LIMITED (JP) 1986-03-12 EP disclosed
EP-0123948-A1 External pharmaceutical composition TEIJIN LIMITED (JP) 1984-11-07 EP disclosed