2,6-Diaminopurine

2,6-Diaminopurine

SCHEMBL28480712

Nc1nc(N)c2[nH]cnc2n1.Nc1ncc2[nH]cnc2n1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.74
PDPK1 O15530 1/20 0.74
GDA Q9Y2T3 1/20 0.74
RXFP1 Q9HBX9 1/20 0.59
CDK2 P24941 8/20 0.51
DPP4 P27487 1/20 0.51
MAP3K5 Q99683 1/20 0.47
KDM4E B2RXH2 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
CDK1 P06493 7/20 0.44
CCNB1 P14635 7/20 0.44
CCNA2 P20248 7/20 0.44
CCNA1 P78396 7/20 0.44
PI4KA P42356 2/20 0.43
PI4K2B Q8TCG2 2/20 0.43
PI4K2A Q9BTU6 2/20 0.43
PI4KB Q9UBF8 2/20 0.43
LMNA P02545 1/20 0.43
DRD3 P35462 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Diaminopurine SCHEMBL24053 0.86 PDPK1 (1.00) PDPK1GDACDK2DPP4MAP3K5
2-Aminopurine SCHEMBL5634 0.86 ALDH1A1 (1.00) ALDH1A1PDPK1GDARXFP1CDK2
2-Aminopurine SCHEMBL3506551 0.84 ALDH1A1 (0.70) ALDH1A1PDPK1GDARXFP1CDK2
2,6-Diaminopurine SCHEMBL27891733 0.84 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL28206545 0.84 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL8757979 0.84 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2-Aminopurine SCHEMBL31379734 0.84 ALDH1A1 (0.96) ALDH1A1PDPK1GDARXFP1CDK2
2-Aminopurine SCHEMBL357699 0.84 ALDH1A1 (0.96) ALDH1A1PDPK1GDARXFP1CDK2
2-Aminopurine SCHEMBL29056388 0.84 ALDH1A1 (0.96) ALDH1A1PDPK1GDARXFP1CDK2
2-Aminopurine SCHEMBL3144589 0.84 ALDH1A1 (0.96) ALDH1A1PDPK1GDARXFP1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111744019-B Mannose-based mRNA targeted delivery system and application thereof 深圳瑞吉生物科技有限公司 2023-08-04 CN claimed
CN-114929244-A Mannose-based mRNA targeted delivery system and application thereof 深圳市瑞吉生物科技有限公司 2022-08-19 CN claimed
CN-111744019-A Mannose-based mRNA (messenger ribonucleic acid) targeted delivery system and application thereof 深圳市瑞吉生物科技有限公司 2020-10-09 CN claimed
CN-111744019-B Mannose-based mRNA targeted delivery system and application thereof 深圳瑞吉生物科技有限公司 2023-08-04 CN disclosed
CN-114929244-A Mannose-based mRNA targeted delivery system and application thereof 深圳市瑞吉生物科技有限公司 2022-08-19 CN disclosed
CN-112005115-A Methods of characterizing multiple analytes from a single cell or cell population 10X基因组学有限公司 2020-11-27 CN disclosed
CN-111744019-A Mannose-based mRNA (messenger ribonucleic acid) targeted delivery system and application thereof 深圳市瑞吉生物科技有限公司 2020-10-09 CN disclosed