SCHEMBL2848082

SCHEMBL2848082

CO/C=C(/C(=O)O)c1ccccc1Oc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
FFAR1 O14842 2/20 0.47
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
ALDH1A1 P00352 2/20 0.45
LPAR1 Q92633 1/20 0.43
LPAR5 Q9H1C0 1/20 0.43
LPAR3 Q9UBY5 1/20 0.43
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
POLB P06746 1/20 0.42
MCL1 Q07820 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
RAB9A P51151 1/20 0.41
F10 P00742 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848088 1.00 KDM4E (0.51) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL203583 0.91 KDM4E (0.47) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL9155033 0.91 KDM4E (0.47) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL29359032 0.91 KDM4E (0.47) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL2848086 0.90 KDM4E (0.54) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL8899456 0.86 KDM4E (0.42) KDM4EFFAR1KMT2AMEN1ALDH1A1
SCHEMBL9420381 0.85 KDM4E (0.46) KDM4EKMT2AMEN1ALDH1A1MAPT
SCHEMBL9420378 0.85 KDM4E (0.46) KDM4EKMT2AMEN1ALDH1A1MAPT
SCHEMBL9151205 0.83 SMN1; SMN2 (0.45) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL9151208 0.83 SMN1; SMN2 (0.45) KMT2AMEN1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 US disclosed
CN-114340374-B Sowing device and method for treating seeds during planting 先正达参股股份有限公司 2024-06-11 CN disclosed
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
CN-111303116-B Microbiocidal heterobicyclic derivatives 先正达参股股份有限公司 2023-10-10 CN disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 EP disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 US disclosed
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-08-25 US disclosed
US-6893651-B1 Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants BAYER AKTIENGESELLSCHAFT (DE) 2005-05-17 US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 US disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US disclosed
EP-0415569-A2 Agrochemical compositions ZENECA LIMITED (GB) 1991-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 KDM4E 3852/4885FFAR1 942/4885KMT2A 2752/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 KDM4E 3852/4885FFAR1 942/4885KMT2A 2752/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG KDM4E 3260/4885FFAR1 648/4885KMT2A 4259/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 KDM4E 2885/4885FFAR1 1006/4885KMT2A 3061/4885
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors CHRNG, CHRM3, CHRNE KDM4E 1928/4885FFAR1 132/4885KMT2A 1952/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 KDM4E 2969/4885FFAR1 169/4885KMT2A 4113/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 KDM4E 4050/4885FFAR1 783/4885KMT2A 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.