Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	5/20	0.50

▸	ALDH1A1	P00352	4/20	0.50

▸	THRB	P10828	3/20	0.50

▸	CYP3A4	P08684	3/20	0.50

▸	RECQL	P46063	2/20	0.50

▸	HPGD	P15428	2/20	0.50

▸	ALOX15	P16050	1/20	0.50

▸	CASP1	P29466	1/20	0.50

▸	HSD17B10	Q99714	1/20	0.50

▸	MEN1	O00255	2/20	0.39

▸	MAPT	P10636	2/20	0.39

▸	RAB9A	P51151	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	POLB	P06746	1/20	0.39

▸	APEX1	P27695	1/20	0.39

▸	BLM	P54132	1/20	0.39

▸	MCL1	Q07820	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	L3MBTL1	Q9Y468	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3818037	0.87	TSHR (0.39)	TSHRALDH1A1THRBCYP3A4RECQL
Sulfuric Acid SCHEMBL5914638	0.72	ALDH1A1 (0.48)	TSHRALDH1A1THRBCYP3A4RECQL
Sulfuric Acid SCHEMBL9103041	0.71	ALDH1A1 (0.48)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL17649942	0.71	TSHR (0.40)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL27374187	0.70	CA1 (0.43)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL4843937	0.70	ALOX15 (0.43)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL3574434	0.69	DPP4 (0.47)	TSHRALDH1A1THRBRECQLHPGD
SCHEMBL11097853	0.69	ALDH1A1 (0.47)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL18444056	0.69	ALDH1A1 (0.41)	TSHRALDH1A1THRBCYP3A4RECQL
SCHEMBL11571432	0.69	ALDH1A1 (0.43)	TSHRALDH1A1THRBCYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112047804-B	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2023-06-27	—	—	CN	claimed
CN-112047804-A	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2020-12-08	—	—	CN	claimed
CN-112028736-A	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2020-12-04	—	—	CN	claimed
CN-112047804-B	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2023-06-27	—	—	CN	disclosed
CN-112047804-A	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2020-12-08	—	—	CN	disclosed
CN-112028736-A	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2020-12-04	—	—	CN	disclosed
CN-112028736-A	Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound	内蒙古永太化学有限公司	2020-12-04	—	—	CN	disclosed