SCHEMBL305032

SCHEMBL305032

CC(C)(C)OC(=O)[C@H](N)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 3/20 0.44
AAK1 Q2M2I8 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
AOC3 Q16853 1/20 0.41
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 1/20 0.40
LTA4H P09960 1/20 0.40
SLC7A5 Q01650 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065221 1.00 L3MBTL1 (0.45) L3MBTL1ATMKMT2AAAK1CTSS
SCHEMBL594359 1.00 L3MBTL1 (0.45) L3MBTL1ATMKMT2AAAK1CTSS
Hydrochloric Acid SCHEMBL304679 0.98 ATM (0.44) L3MBTL1ATMKMT2AAAK1CTSS
Hydrochloric Acid SCHEMBL595486 0.98 ATM (0.44) L3MBTL1ATMKMT2AAAK1CTSS
Hydrochloric Acid SCHEMBL628345 0.98 ATM (0.44) L3MBTL1ATMKMT2AAAK1CTSS
SCHEMBL6606388 0.86 ATM (0.41) L3MBTL1ATMKMT2AAAK1CTSS
SCHEMBL1925699 0.86 ATM (0.41) L3MBTL1ATMKMT2AAAK1CTSS
SCHEMBL27636817 0.86 ATM (0.41) L3MBTL1ATMKMT2AAAK1CTSS
SCHEMBL30745061 0.84 ALDH1A1 (0.44) L3MBTL1ATMKMT2ANPSR1CYP1A2
SCHEMBL506934 0.84 ANPEP (0.45) KMT2AAAK1CYP1A2SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12098153-B2 Small molecule inhibitors targeting Clostridioides difficile sporulation UNIVERSITY OF SOUTH FLORIDA (US) 2024-09-24 US disclosed
US-20240051959-A1 SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION UNIVERSITY OF SOUTH FLORIDA 2024-02-15 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-11814385-B2 Small molecule inhibitors targeting Clostridioides difficile sporulation UNIVERSITY OF SOUTH FLORIDA (US) 2023-11-14 US disclosed
US-20230002381-A1 SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION NATIONAL INSTITUTES OF HEALTH 2023-01-05 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-11091442-B2 Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-08-17 US disclosed
US-11046653-B2 2021-06-29 US disclosed
US-20200369619-A1 FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2020-11-26 US disclosed
WO-2008021936-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
WO-2008021936-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
WO-2008021928-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
WO-2008021928-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
WO-2008021927-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
WO-2008021927-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
US-20080044379-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2008-02-21 US disclosed
EP-1345918-B1 1,5 BENZOTHIAZEPINES AND THEIR USE AS ANTIHYPERLIPIDEMICS ASTRAZENECA AB (SE) 2007-04-18 EP disclosed
US-7192945-B2 Benzothiazepine derivatives ASTRAZENECA AB (SE) 2007-03-20 US disclosed
US-20040067933-A1 Chemical compounds ELOBIX AB (SE) 2004-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067933-A1 Chemical compounds SLC10A2, SLC10A1, ABCB11 L3MBTL1 2907/4885ATM 4389/4885KMT2A 2975/4885
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS L3MBTL1 4285/4885ATM 234/4885KMT2A 4371/4885
US-11046653-B2 CYP4F11, NOTUM, CYP2F1 L3MBTL1 3471/4885ATM 4085/4885KMT2A 1205/4885
US-20080044379-A1 Hepatitis C Virus Inhibitors HAVCR2, PYGL, HCCS L3MBTL1 3763/4885ATM 3538/4885KMT2A 4516/4885
US-20230002381-A1 SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION SPOUT1, CLPP, RPN2 L3MBTL1 4576/4885ATM 1771/4885KMT2A 4130/4885
US-11814385-B2 Small molecule inhibitors targeting Clostridioides difficile sporulation SPOUT1, CLPP, RPN2 L3MBTL1 4576/4885ATM 1771/4885KMT2A 4130/4885
US-20200369619-A1 FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF WEE1, NOTUM, WEE2 L3MBTL1 1956/4885ATM 4159/4885KMT2A 950/4885
US-11091442-B2 Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof WEE1, NOTUM, WEE2 L3MBTL1 1956/4885ATM 4159/4885KMT2A 950/4885
US-20240051959-A1 SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION SPOUT1, CLPP, RPN2 L3MBTL1 4576/4885ATM 1771/4885KMT2A 4130/4885
US-12098153-B2 Small molecule inhibitors targeting Clostridioides difficile sporulation SPOUT1, CLPP, RPN2 L3MBTL1 4576/4885ATM 1771/4885KMT2A 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.