Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497974 | 0.81 | ALPL (0.33) | ALPLALDH1A1HPGDUSP2LMNA | |
| SCHEMBL7592335 | 0.75 | ALDH1A1 (0.36) | ALPLALDH1A1HPGDUSP2LMNA | |
| SCHEMBL20668745 | 0.72 | ALDH1A1 (0.42) | ALPLALDH1A1HPGDLMNAGAA | |
| SCHEMBL28184067 | 0.71 | GAA (0.31) | ALPLGAA | |
| SCHEMBL16019755 | 0.70 | ALDH1A1 (0.41) | ALPLALDH1A1HPGDLMNAGAA | |
| SCHEMBL595428 | 0.69 | ALDH1A1 (0.48) | ALPLALDH1A1HPGDLMNAGAA | |
| SCHEMBL16019754 | 0.66 | ALDH1A1 (0.45) | ALPLALDH1A1HPGDLMNAGAA | |
| SCHEMBL11354287 | 0.66 | ALDH1A1 (0.44) | ALPLALDH1A1HPGDLMNAGAA | |
| SCHEMBL13464342 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAGAAKDM4E | |
| SCHEMBL29388389 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978328-B | Synthesis method of ticagrelor | 南京一心和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111978327-B | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111978328-A | Synthesis method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111978327-A | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |