Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863131 | 0.92 | CNR1 (0.50) | CNR1MAPTTAAR1CCR1ABCB1 | |
| SCHEMBL2850314 | 0.92 | P2RX7 (0.42) | CNR1MAPTTAAR1CCR1NPSR1 | |
| SCHEMBL2859429 | 0.91 | NPC1 (0.46) | MAPTTAAR1NPSR1GAANPC1 | |
| SCHEMBL2855623 | 0.91 | CCR1 (0.44) | CNR1MAPTCCR1ABCB1NPSR1 | |
| SCHEMBL2860669 | 0.89 | TAAR1 (0.46) | CNR1MAPTTAAR1CCR1ABCB1 | |
| SCHEMBL2854891 | 0.88 | ABCB1 (0.52) | CNR1ABCB1GAATP53 | |
| SCHEMBL2855547 | 0.86 | TAAR1 (0.54) | CNR1MAPTTAAR1CCR1ABCB1 | |
| SCHEMBL2857600 | 0.85 | CNR1 (0.46) | CNR1MAPTTAAR1CCR1ABCB1 | |
| SCHEMBL2852505 | 0.85 | ABCB1 (0.48) | CNR1MAPTTAAR1CCR1ABCB1 | |
| SCHEMBL2853462 | 0.85 | TRPV1 (0.42) | CNR1MAPTTAAR1CCR1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |