Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852556 | 0.92 | TDP1 (0.44) | MAPTPOLBTP53CCR1NPC1 | |
| SCHEMBL2848475 | 0.92 | CNR1 (0.48) | P2RX7MAPTTP53CCR1NPC1 | |
| SCHEMBL2859429 | 0.92 | NPC1 (0.46) | MAPTPOLBNPC1GAARAB9A | |
| SCHEMBL2856797 | 0.91 | P2RX7 (0.45) | P2RX7CCR1ALDH1A1L3MBTL1SMO | |
| SCHEMBL2863154 | 0.88 | MAPT (0.45) | P2RX7MAPTTP53CCR1ALDH1A1 | |
| SCHEMBL2857856 | 0.88 | TSHR (0.49) | MAPTALDH1A1TSHR | |
| SCHEMBL2854346 | 0.85 | MAPT (0.52) | P2RX7MAPTPOLBTP53CCR1 | |
| SCHEMBL2855711 | 0.85 | P2RX7 (0.42) | P2RX7MAPTTP53CCR1SMO | |
| SCHEMBL2852633 | 0.85 | TAAR1 (0.57) | MAPTTP53NPC1GAARAB9A | |
| SCHEMBL2862820 | 0.85 | P2RX7 (0.45) | P2RX7MAPTCCR1L3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |