Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850871 | 0.91 | NPC1 (0.51) | RAB9ANPC1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2852552 | 0.91 | MEN1 (0.51) | RAB9ANPC1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2854596 | 0.90 | TP53 (0.46) | NPSR1MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2859508 | 0.89 | CYP1A2 (0.46) | RAB9ANPC1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2857550 | 0.88 | TMPRSS4 (0.45) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| SCHEMBL2858182 | 0.88 | P2RX7 (0.44) | RAB9ANPC1NPSR1MAPTPOLB | |
| SCHEMBL2855775 | 0.88 | P2RY1 (0.44) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL2853182 | 0.88 | MAPT (0.42) | RAB9ANPC1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2850610 | 0.87 | MAPT (0.40) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL2857353 | 0.87 | CCR1 (0.47) | MAPTSMN1; SMN2POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |