Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860786 | 0.94 | MAPT (0.49) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854516 | 0.93 | P2RX7 (0.46) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854596 | 0.91 | TP53 (0.46) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2848541 | 0.91 | RAB9A (0.43) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2859508 | 0.90 | CYP1A2 (0.46) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854533 | 0.89 | MEN1 (0.46) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2855775 | 0.89 | P2RY1 (0.44) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2850610 | 0.88 | MAPT (0.40) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854497 | 0.87 | NPY5R (0.44) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2857074 | 0.87 | LPAR1 (0.42) | MEN1KMT2AMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |