Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850610 | 0.93 | MAPT (0.40) | TP53GAAKDM4EALDH1A1NR3C1 | |
| SCHEMBL2857574 | 0.91 | MAPT (0.50) | KDM4EALDH1A1NR3C1MAPTPOLB | |
| SCHEMBL2857353 | 0.91 | CCR1 (0.47) | TP53GAAKDM4EALDH1A1MAPT | |
| SCHEMBL2852552 | 0.91 | MEN1 (0.51) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2848541 | 0.90 | RAB9A (0.43) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2859508 | 0.89 | CYP1A2 (0.46) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2855775 | 0.88 | P2RY1 (0.44) | TP53GAAKDM4EALDH1A1NR3C1 | |
| SCHEMBL2852820 | 0.87 | TMPRSS4 (0.45) | TP53ALDH1A1MAPTCCR1HTT | |
| SCHEMBL2857074 | 0.86 | LPAR1 (0.42) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2858110 | 0.86 | KDM4E (0.44) | GAAKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |