Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473504 | 0.77 | SMN1; SMN2 (0.51) | GAAALDH1A1RAB9AALOX15KMT2A | |
| SCHEMBL28480981 | 0.77 | MEN1 (0.46) | GAAALDH1A1RAB9AHSP90AA1ALOX15 | |
| SCHEMBL28477954 | 0.76 | KAT8 (0.65) | GAAKDM4EALKBH3 | |
| SCHEMBL28482422 | 0.74 | RAB9A (0.50) | GAAALDH1A1RAB9AALOX15KMT2A | |
| SCHEMBL1562741 | 0.73 | ALDH1A1 (0.59) | GAAALDH1A1RAB9AHSP90AA1KMT2A | |
| SCHEMBL28345334 | 0.73 | MPI (0.64) | GAAALDH1A1RAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL1114873 | 0.73 | HSP90AA1 (0.46) | GAAALDH1A1RAB9AHSP90AA1KMT2A | |
| SCHEMBL11410044 | 0.73 | TSHR (0.64) | GAAALDH1A1RAB9AHSP90AA1KMT2A | |
| SCHEMBL12660996 | 0.64 | HSP90AA1 (0.55) | GAAALDH1A1RAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL24445253 | 0.64 | HTR3A (0.43) | GAAALDH1A1RAB9AHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970752-B | Synthesis method of chiral 4-spiro pyrazole compound | 浙江工业大学 | 2020-11-13 | — | — | CN | disclosed |