Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487170 | 0.92 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22673718 | 0.83 | HPGD (0.48) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1841156 | 0.76 | ALDH1A1 (0.59) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6197818 | 0.76 | ALDH1A1 (0.59) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16597715 | 0.75 | TSHR (0.49) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22673922 | 0.73 | KMT2A (0.47) | ALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL22673801 | 0.73 | MEN1 (0.53) | HPGDALDH1A1NPC1TSHR | |
| SCHEMBL22673848 | 0.71 | MEN1 (0.49) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22673933 | 0.71 | NPSR1 (0.46) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL250325 | 0.70 | NOTUM (0.58) | HPGDALDH1A1SMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909133-A | Substituted 1-amino-1H-imidazole-5-carboxamides as brunauer tyrosine kinase inhibitors | 河南师范大学 | 2020-11-10 | — | — | CN | disclosed |