Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18191032 | 0.99 | HRH3 (0.44) | HRH3TSHRSMN1; SMN2TAOK1TAOK3 | |
| SCHEMBL18197821 | 0.93 | HRH3 (0.43) | HRH3TSHRSMN1; SMN2TAOK1TAOK3 | |
| SCHEMBL14703141 | 0.86 | EPHX2 (0.48) | HRH3TSHRSMN1; SMN2TAOK1TAOK3 | |
| SCHEMBL14703147 | 0.85 | EPHX2 (0.47) | HRH3TSHRSMN1; SMN2TAOK1TAOK3 | |
| SCHEMBL20023235 | 0.85 | SCN3A (0.37) | LMNAEPHX2TRPV1 | |
| SCHEMBL23935877 | 0.85 | METAP2 (0.42) | LMNAPOLBMEN1KMT2AP2RX7 | |
| SCHEMBL18191042 | 0.81 | TGM2 (0.38) | SMN1; SMN2LMNA | |
| SCHEMBL23935916 | 0.80 | METAP2 (0.42) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL18190981 | 0.80 | MTOR (0.39) | SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL28487662 | 0.79 | HRH3 (0.46) | HRH3TSHRSMN1; SMN2TAOK1TAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | disclosed |