Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23935877 | 0.86 | METAP2 (0.42) | METAP2ROCK2CHRM3CHRM2POLB | |
| SCHEMBL18190981 | 0.86 | MTOR (0.39) | POLBMAPTMEN1KMT2A | |
| SCHEMBL19393859 | 0.84 | MEN1 (0.44) | METAP2MMP13CHRM3GFERPOLB | |
| SCHEMBL28487664 | 0.80 | HRH3 (0.45) | POLBALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18191032 | 0.79 | HRH3 (0.44) | POLBALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL18191042 | 0.78 | TGM2 (0.38) | — | |
| SCHEMBL18197810 | 0.78 | MLYCD (0.41) | CYP2D6MEN1KMT2A | |
| Acetic Acid SCHEMBL18190974 | 0.75 | FPR2 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23935878 | 0.75 | — | — | |
| SCHEMBL18191058 | 0.74 | ANPEP (0.36) | ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |