Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23935916 | 0.86 | METAP2 (0.42) | METAP2MAPTKMT2AMEN1POLB | |
| SCHEMBL18190981 | 0.86 | MTOR (0.39) | MAPTKMT2AMEN1POLB | |
| SCHEMBL28487664 | 0.85 | HRH3 (0.45) | P2RX7KMT2AMEN1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL18191032 | 0.84 | HRH3 (0.44) | KMT2AMEN1LMNAPOLB | |
| SCHEMBL17777323 | 0.83 | KMT2A (0.44) | PKMMAPTKMT2AMEN1LMNA | |
| Acetic Acid SCHEMBL18190965 | 0.81 | SMN1; SMN2 (0.40) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL18197821 | 0.78 | HRH3 (0.43) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL18191042 | 0.78 | TGM2 (0.38) | LMNA | |
| SCHEMBL18197810 | 0.78 | MLYCD (0.41) | PKMKMT2AMEN1 | |
| SCHEMBL20023235 | 0.78 | SCN3A (0.37) | LMNAROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |