Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487664 | 0.93 | HRH3 (0.45) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18191032 | 0.92 | HRH3 (0.44) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| SCHEMBL14703141 | 0.82 | EPHX2 (0.48) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| SCHEMBL14703147 | 0.81 | EPHX2 (0.47) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| SCHEMBL18197800 | 0.81 | MTOR (0.38) | HRH3ALDH1A1AKT2CA1CA2 | |
| SCHEMBL28494767 | 0.80 | HRH3 (0.44) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28489073 | 0.79 | HRH3 (0.43) | HRH3TAOK1TAOK3TSHRSMN1; SMN2 | |
| SCHEMBL18197810 | 0.79 | MLYCD (0.41) | HRH3TSHRMEN1KMT2ATRPV1 | |
| SCHEMBL20023235 | 0.79 | SCN3A (0.37) | LMNAEPHX2TRPV1 | |
| SCHEMBL23935877 | 0.78 | METAP2 (0.42) | LMNAPOLBMEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| WO-2016175357-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | HRH3 4706/4885TAOK1 3254/4885TAOK3 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.